ALINESS NMN with Resveratrol 300mg/100mg (NAD+ Precursor, DNA Repair) 30 Vegan Capsules

Nicotinamide mononucleotide (NMN) is a naturally occurring metabolite of niacin, or Vitamin B3, in the body. However, the NMN molecule has a much more complex structure than niacin, as it is a combination of three compounds - nicotinic acid amide, ribose and phosphoric acid. The characteristic molecular structure means that in the body NMN is used as a precursor of NAD+, which is the primary fuel for processes taking place inside mitochondria and also a cofactor for important functional proteins such as sirtuins or PARP proteins involved in DNA regeneration and repair.

That's why nicotinamide mononucleotide has recently attracted increasing interest and is becoming one of the leading trends in the anti-aging field, especially those related to the body's internal, cellular regeneration.

• UTHEVER®. Scientifically verified safety and efficacy!
• UTHEVER® is the world's first and only NMN that has been so extensively and comprehensively studied. According to WHO and US government clinical databases, clinical research on UTHEVER® is on the largest scale of any other NMN under study.*

CLINICAL TRIAL
A multicenter, randomized, double-blind, parallel, placebo-controlled study to evaluate the efficacy and safety of NMN UTHEVER® for oral supplementation in middle-aged and elderly people

BACKGROUND: The study was conducted on 66 healthy subjects between the ages of 40 and 65, who were instructed to take two capsules (each containing 150 mg of NMN or starch powder) once daily after breakfast for 60 days.

Results: On day 30, serum NAD+/NADH levels showed a significant increase, i.e. 11.3%, while the placebo group showed no change. At the end of the study, i.e. day 60, NAD+/NADH levels increased further by 38% compared to baseline, compared to only 14.3% in the placebo group. At the end of the study, the mean insulin resistance index (HOMA IR) showed an increase of 0.6% in the Uthever® group and 30.6% in the placebo group, compared to baseline.

Conclusions: The increase in NAD+/NADH levels at day 30 and 60 illustrated the potential of UTHEVER® to increase cellular NAD+ levels, which is associated with higher energy levels and anti-aging effects. Increased insulin sensitivity has also been linked to anti-aging.

https://www.frontiersin.org/articles/10.3389/fragi.2022.851698/full
https://clinicaltrials.gov/ct2/show/NCT04228640