THORNE RESEARCH Perfusia Plus (Heart and circulatory system) 180 Vegetarian capsules

Supports heart and blood flow by combining L-arginine with nutrients, antioxidants, and botanicals.
Perfusia Plus combines sustained-release L-arginine, which provides cardiovascular benefits by promoting nitric oxide production in the arteries, with nutrients and botanicals to support optimal blood flow, including penile blood flow.


Significant research supports the cardiovascular benefits of L-arginine in promoting vascular health and blood flow. L-arginine enhances nitric oxide production in the arteries, which in turn relaxes blood vessels and maintains healthy blood flow. Perfusia Plus combines sustained-release L-arginine with nutritional cofactors that enhance nitric oxide synthesis in the blood vessels (5-MTHF and ascorbic acid), in addition to antioxidants and botanicals that promote normal blood flow (R-lipoic acid, green tea extract, and resveratrol).


L-arginine is a semi-essential amino acid that is involved in multiple areas of human physiology and metabolism. It has a significant effect on endocrine function and helps regulate the release of neurotransmitter chemicals, insulin, glucagon (which has the opposite effect of insulin; i.e., it raises blood sugar), and growth hormone.* However, one of L-arginine's most compelling contributions to human physiology is its role as a biological precursor of nitric oxide. The lining of the arteries (the vascular endothelium) creates nitric oxide from L-arginine, resulting primarily in the relaxation of the blood vessels. This process is important to maintaining good vascular health, heart health, reproductive health, and protection against oxidative damage.


Maintaining the healthy vascular endothelium function depends on an adequate supply of L-arginine being available to these cells. Without adequate L-arginine – and the subsequent production of nitric oxide – available to the vascular endothelium, arteries don't optimally dilate, which results in less than optimal blood flow to the organs and extremities.


A recent study demonstrated blood flow improvement after Perfusia supplementation in individuals who had less than optimum heart health. In another study, after Perfusia was given to 29 healthy volunteers for one week, significant support for a healthy cardiovascular system was observed.


Studies on Perfusia show increased blood flow to the heart muscle and the extremities, maintenance of already normal blood pressure, and improved vascular elasticity.


In a large, double-blind clinical trial that studied male reproductive health issues, 1.6 grams of L-arginine given daily for six weeks resulted in improvements in reproductive health in men who previously had low nitric oxide metabolism.


Like most amino acids, L-arginine is a building block for proteins; however, its presence also appears to support wound healing. Numerous studies indicate L-arginine supplementation benefits wound healing time and tissue strength in and around a wound during the healing phase.