THORNE RESEARCH Phytisone (Adrenal Support) 60 Vegetarian Capsules

Helps manage the effects of stress and reduce fatigue.
Phytisone is a unique, non-glandular formula of botanicals and nutrients to help optimize the adrenal gland's response to stress.


When humans encounter a threat, the adrenal glands release cortisol, epinephrine, norepinephrine, and other chemicals that raise our heart rate, blood pressure, and blood sugar, and constrict blood vessels to the digestive tract. This "fight or flight" reflex can be a life saver. However, the constant low-level stress most of us feel today, together with environmental pollution and diets that are high in refined carbohydrates, can overstimulate and overtax the adrenal glands, which can damage our immune, cardiovascular, neurological, and endocrine systems, and thus our long-term health. Phytisone provides botanical, non-glandular support for the adrenal glands. Its unique combination of key adaptogen botanicals and nutrients help the adrenals optimize their response to stress.


Astragalus membranaceus is used – typically in combination with ginseng – to promote energy and support immune function. Licorice root (Glycyrrhiza glabra) appears to have a modulating effect on cortisol activity. Ginger (Zingiber officinale) has the capacity to increase the absorption of other substances. Perhaps the two best-known adaptogens (substances that improve the body's resistance to stress) are Panax ginseng and Eleutherococcus senticosus. An abundance of research demonstrates an enhanced response to physical and chemical stress, as well as a beneficial physiological effect on the central nervous, cardiovascular, and endocrine systems, following administration of Panax ginseng. Similarly, ample evidence supports the use of Eleutherococcus to help normalize the body's response to stress. Ashwagandha (Withania somnifera) – often called Indian ginseng – is considered to be the preeminent adaptogen from the Ayurvedic medical system. Ascorbic acid, thiamine (vitamin B1), pantethine (the active form of vitamin B5), pyridoxal 5'-phosphate (the active form of vitamin B6), and zinc are included in Phytisone for their strengthening and supportive role in optimizing adrenal function.