Hashimoto - co wiemy o tej chorobie?

HASHIMOTO - WHAT DO WE KNOW ABOUT THIS DISEASE?

Thyroid is a gland found in the human body. Its proper operation creates numerous effects on the functioning of the entire organism. When its functioning is disturbed, complications occur very quickly, which leave their mark on the general condition of a person. If there are problems with the thyroid gland, the heart rhythm is disturbed, the work of the ovaries is dysregulated, which results in irregular menstruation.

Although these are internal effects, Hashimoto's can be recognized by the external condition of the body. The skin and hair lose their glow, become dry and even fall out. Alopecia leads to the malaise of sick people, because it mainly affects middle-aged women. Not only are they at risk of menopause, they also have a problem with hair loss. For this reason, Hashimoto's disease can burden our body even more.

HASHIMOTO - WHAT IS THIS?

Hashimoto's is the most common type of thyroiditis. Information about its course comes from many sources. This disease can be considered as the primary cause of hypothyroidism. Very often, the condition occurs in conjunction with other autoimmune problems.

It can be indicated that is formed as a result of spreading lymphatic infiltration within the thyroid gland with centers of embryonic development . The next step is fibrosis and atrophy of the thyroid parenchyma. Occasionally there are eosinophilic changes in the follicular cells of the thyroid gland. At present, it is one of the most common autoimmune and endocrine diseases and the main cause of hypothyroidism.

Concerning certain genetic predispositions, “Hashimoto disease” affects women more often than men. In turn, in the case of age, it is assumed that the prevalence oscillates around 2% in each age category, however, the group in which this disease occurs most often are people between 45 and 65 years of age. In terms of race, the disease is much more common in Caucasians than in Asians and African Americans.

HASHIMOTO CAUSES AND SYMPTOMS

>Hashimoto's disease has an autoimmune background and is closely related to human immunity. Thyroid gland disorders may result from genetic factors or stress. Unfortunately, there is no unambiguous theory that indicates the origin of Hashimoto's. There is a moment when the thyroid becomes inflamed and destroyed. This inflammation is caused by the body's own cells attacking the organ. This process is long-lasting, hence the sick person is not aware of the upcoming threat. There are no symptoms until the thyroid is compromised enough to show immediate symptoms.

Hashimoto's symptoms yields different. They are most often revealed during other tests, often those which result from health problems that, at first glance, are in no way directly related to the work and functioning of the thyroid gland. Such a case may be problems with getting pregnant, which are initially justified by other ailments, e.g. menstrual irregularity,  dizziness or cardiac disorders, when the real cause is Hashimoto's disease. Hashimoto's is often asymptomatic at the beginning of the disease.

It cannot be ruled out that Hashimoto's disease will be evidenced by everyday muscle pain and joints and breathing difficulties, combined with a feeling of intense fatigue, despite little effort.

It should also be pointed out that weight gain or weight gain itself may also have its source in the work of the thyroid gland . However, each of us initially (which seems completely understandable) equates this problem with “bad conduct” i.e.  physical inactivity and poor eating habits.

The occurrence of Hashimoto's disease, which has its genesis in improper thyroid function , i.e. hypothyroidism,may be affected by previously passed viral diseases that weaken our body and cause numerous diseases. There may also be other reasons, which are discussed below.

Hashimoto's symptoms:

• TPO antibody concentration of at least 500,
• TSH levels above standard amounts,
• hypoechoic parenchyma during ultrasound examination,
• other symptoms of hypothyroidism or hyperthyroidism;.         
   

EXTERNAL FACTORS AND HASHIMOTO           

Disclosure of genetic predisposition to Hashimoto's disease may be based on environmental factors.

In this case, we can distinguish the following components, which to a certain extent affect the creation of this disease:

• excess iodine in the body,
• bacterial and viral infections (Coxsackie B virus, retroviruses, Helicobacter pylori, Yersinia enterocolitica, Borrelia burgdorferi, and hepatitis C virus),
• nicotine addiction,       
• exposure to stressors,
• using the following medications:     
       *amiodarone,
       *lithium salts,     
       *interferon α,         
       *interleukins.
   

It is necessary to point out that the cause of Hashimoto's disease is the immune system. This system requires efficient and correct regulation of cell transport to target tissues and organs. The right signals to attract effector and regulatory cells are provided by the chemoic system. It consists of small molecule proteins from the group of cytokines that are secreted by cells (chemoattractant cytokines). Their function is to induce migration or chemotaxis of many types of cells.

In this case, the following cells are indicated:

• neutrophils,     
• monocyte,
• lymphocytes,  
• eosinophils,    
• fibroblasts and keratinocytes.

They go to  thyroid gland.

Proper recognition of the correct epitopes on the endothelium of blood vessels and on inflammatory cells leads to the release of chemokines. As a result, the first wave of effector cells that are involved in the immune response is attracted.  When lymphocytes are activated, antigen-specific effector T cells are attracted to the inflammatory focus.  Regulatory cells and effectors, which creates a local inflammatory process. Autoimmune thyroiditis can be serious. It is therefore worth conducting appropriate research.

HASHIMOTO – WHAT RESEARCH?

The most important thing before taking the right treatment is of course making the right diagnosis. In the context of Hashimoto's disease, this comes down to an earlier examination of the neck, the so-called palpation, which allows you to determine the size of the thyroid gland in the body.  If after the examination it turns out that the gland is smaller than it should be, the next step will be a blood test.

Blood Analysis and the information obtained from it will allow you to determine the level of thyroid hormone TSH (thyroxine) present in it. Determining, or rather finding a low level of this hormone, determines further tests, i.e. testing free thyroid hormones or anti-thyroid antibodies. To the group of studies allowing to identify  a phenomenon called Hashimoto's disease, also includes an ultrasound examination of the thyroid gland for a thorough inspection of the gland and possible disclosure of nodules in it.

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HASHIMOTO – COURSE OF THE DISEASE

Being diagnosed with Hashimoto's leads to a steady progression of hypothyroidism. However, there is no one-size-fits-all pattern of behavior here, as the thyroid gland is generally reduced in size during illness, however, there are cases where the opposite is true – is growing. Ultrasound examination of the thyroid gland allows you to see its nodules, but the situation in which Hashimoto's disease leads to cancer of the lymph tissue, which is manifested by a significant enlargement of the thyroid gland, is quite a rare phenomenon. It should also be emphasized that Hashimoto's disease, despite some changes in the functioning and work of the thyroid gland, does not have to develop at all, as long as the hormone levels in the body are still normal. In this situation, it is the duty to constantly control and supervise whether this state does not change.

HASHIMOTO - TREATMENT

There are many ways to treat Hashimoto's disease – it all depends on the development of the disease and its intensity, e.g. chronic thyroiditis. In the initial phase, treatment should consist of taking anti-inflammatory drugs along with levothyroxine, which contains thyroid hormone. It should be remembered that the tablets are taken on an empty stomach, and after their consumption it is recommended to take a break of several dozen minutes from meals. Using the dose recommended by doctors, you should not be afraid of any undesirable effects when taking these drugs, because the body is highly tolerant in their case.

Unfortunately, this method of treatment will not lead to a complete cure, moreover, the drugs must be taken until death, and the dose of thyroxine depends on the degree of thyroid damage. Thus, in order to be able to correctly determine the correct dose, it is necessary to perform control tests once every 3–6 months to determine the amount of thyroxine in the blood.

It needs to be emphasized, which will serve as a warning that treatment of Hashimoto's disease, or rather lack thereof, may cause heart problems, overweight or excess cholesterol, as well as affect our mental sphere, causing anxiety, mood disorders, and ultimately depression.
 

Although you may get a different impression, the psychological aspect is extremely important in Hashimoto's disease. Research conducted by scientists clearly shows that people living under constant stress are more susceptible to Hashimoto's disease than people who are not exposed to it. However, it must be remembered that fluctuations in the TSH concentration may also be caused by fluctuations in the acid-base balance.

HASHIMOTO DIET - BASICS

Diet in Hashimoto's plays a very important role. The quality of the products consumed is particularly important. The diet should primarily be rich in products such as goitrogens, also known as "iodine thieves", because these compounds have a high impact on the immune system of people suffering from Hashimoto's disease.

WHAT PRODUCTS TO CONSUME?

Hashimoto's diet must be based on high-fiber foods, as the condition slows down bowel movements. Fiber “forces” intestines to exercise, and also removes toxins from the body and gives us a feeling of satiety.

Products rich in fiber include:

• beets,
• carrot,
• apples,
• bananas,
• avocado,
• sprouts,
• almonds,
• all kinds of whole grains.

Another important element of the Hashimoto's diet is protein - a building block of muscles and cells in our body, helping us maintain the right weight. 

Note that not every protein-rich product will be a good option for Hashimoto's sufferers. Such people should definitely avoid, among others, milk or yogurt, because hypothyroidism is often accompanied by lactose intolerance, which can cause such ailments as unpleasant bloating or the effect of fullness.

People diagnosed with Hashimoto's disease should provide the body with protein mainly in the form of meat, eggs and starch products containing protein.

When setting a diet, one must not forget about products containing goitrogens, which include in particular m .in.:

• broccoli,
• Brussels sprouts,
• horseradish,
• peaches,
• turnip,
• strawberries,
• spinach,
• yams,
• radishes,
• linseed,
•  and bamboo shoots.

Hashimoto's diet should also include good carbs, in this case carbs complex present, for example, in beans, groats or lentils, because taking simple sugars that occur in products such as chocolate bars or chocolate - they are quickly deposited in fat tissue.

It is also worth supplementing your diet with fish, but don't let them be a solution too often, unlike lettuce , fruits and vegetables that we can eat as much as we want, while maintaining common sense.

HASHIMOTO DIET – PRODUCTS NOT ALLOWED

In addition to knowing what products and what nutrients should be provided to the body during Hashimoto's disease, there is also awareness of what you cannot eat. This information is necessary for a proper “fight” with the disease. People with Hashimoto's disease should pay special attention to the labels placed on products, because their diet should contain a certain amount of iodine, which in excess can cause the opposite effect.

Products that should be limited, and preferably completely excluded from the diet are:

• ready sausages – due to the presence of soy in them, which adversely affects people suffering from Hashimoto's disease.
• all soy products, i.e. cutlets, tripe and even oil.
• gluten – gluten intolerance leads to celiac disease, which results in damage to the villi in the intestine, whose task is to absorb and digest the food eaten.
• coffee,
• pepper,
• alcohol,
• teas,
• goji berries,
• tomatoes.

Products that will help your thyroid include:
 

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Thyroset supports the proper functioning of the thyroid gland and the endocrine system. It was developed to supplement the basic deficiencies of vitamins and minerals in people requiring special attention to thyroid health (e.g. people with Hashimoto's disease and hypothyroidism). Remember that supplementation supports, but in itself is not the main therapeutic effect. In the case of deeper deficiencies, it may be necessary to supplement them additionally, determined on the basis of laboratory tests and medical consultation.

NOW FOODS Thyroid Energy (Thyroid Support) - 90 vegetarian capsules




Thyroid Energy is a complete dietary supplement to support a healthy thyroid. Now iodine and tyrosine, two integral components necessary for the synthesis of thyroid secretions, have been combined. The minerals selenium, zinc and copper have been added as cofactors needed for proper thyroid function. In addition, NOW Thyroid Energy contains Ayurvedic herbal extracts of Guggul (Commiphora mukul) and Ashwagandha (Withania somnifera) to replenish nutrients.

THORNE Thyrocsin (Support Healthy Thyroid Function) 120 Vegetarian Capsules



Thorne's Thyrocsin formula contains key ingredients for thyroid support, including iodine, which is essential for T4 formation, and L-tyrosine, which is essential for both T4 and T3 formation. Animal studies have shown that Ayurvedic The botanical, Ashwagandha, may increase T4 concentrations. Thyrocsin also contains several nutrient cofactors necessary to convert T4 to T3, including the minerals selenium, zinc, and copper. Thyrocsin contains vitamin B12, as a deficiency in this vitamin appears to interfere with hormone activity thyroid. T4 to T3 conversion can be inhibited by heavy metal toxicity and lipid peroxidation; hence the inclusion of antioxidant vitamins C and E to offset this inhibition. 
 

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